Development and in vitro evaluation of chitosan-Eudragit RS 30D composite wound dressings
نویسندگان
چکیده
منابع مشابه
Development of antimicrobial chitosan based nanofiber dressings for wound healing applications
Objective(s): Chitosan based composite fine fibers were successfully produced via a centrifugal spinning technology. This study evaluates the ability of the composites to function as scaffolds for cell growth while maintaining an antibacterial activity. Materials and methods: Two sets of chitosan fiber composites were prepared, one filled with anti-microbial silver nanoparticles and another on...
متن کاملEvaluation of the Mechanical Properties and Drug Permeability of Chitosan/Eudragit RL Composite Film
OBJECTIVES The aim of this study was to design and evaluate a chitosan-based film that has properties required for successful wound dressing, and can control drug penetration and maintenance time in the location. METHODS Several formulations of a film containing chitosan (3%) and different concentrations of Eudragit RL (0.5%, 1%, and 1.5%) were prepared using the casting/solvent evaporating t...
متن کاملChitosan-polyethylene glycol coated cotton membranes for wound dressings
Membranes have been developed by coating a blend of chitosan (CS) and polyethylene glycol (PEG) of different molecular weights (4000, 10,000 and 20,000) on cotton fabric followed by freeze drying. The influence of PEG molecular weight on the physical characteristics of the membranes has been investigated. The scanning electron microscopy of the coated fabric reveals porous structure. The porosi...
متن کاملAn overview of modified release chitosan, alginate and eudragit RS microparticles
In this paper, different formulation types of microparticulate systems such as beads, microbeads, microspheres and microsponges using to special attention chitosan, alginate and eudragit RS 100 are reviewed. Chitosan and alginates are natural, anionic or cationic, biocompatible, biodegredable and non-toxic polymers. They have excellent potential for pharmaceutical and biopharmaceutical applicat...
متن کاملPectin/chitosan/Eudragit RS mixed-film coating for bimodal drug delivery from theophylline pellets: preparation and evaluation.
Pellets containing theophylline as a model drug and microcrystalline cellulose, in a ratio of 6:4, were prepared by the extrusion-spheronization method. The pellets were coated with Eudragit RS aqueous dispersions, containing various amounts of pectin-chitosan complex and different coating mass gains, using a fluidized-bed apparatus. Twelve formulations were developed, which differed in two fac...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: AAPS PharmSciTech
سال: 2006
ISSN: 1530-9932
DOI: 10.1208/pt070130